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Description
Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor/TNFRSF12A (Human TWEAK Receptor/TNFRSF12A) _ 90608ESTWEAKR belongs to the TNF family of transmembrane proteins, and contains a cytoplasmic "death domain", which can activate a cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either membrane anchored or soluble TWEAK. Recombinant Human soluble TWEAKR is a 53 amino acid polypeptide (5. 6 kDa) comprising the entire extracellular
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.4 ★★★★★
Based on 2458 reviews
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Product Reviews
★★★★★ 5
Durable
Size: Large(2-Pack), Product Packaging: Standard Packaging
Great quality especially for large dogs. Fill it up and keeps pets busy for hours. Almost all Kong products and perfect for heavy chewers.
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Reviewed in the United States on May 22, 2026
★★★★★ 5
Great for freezing apple sauce, peanut butter, etc for a treat.
Size: Large (Pack of 1), Product Packaging: Standard Packaging
Our dog has extreme separation anxiety. When ever he even thinks we are going to leave he barks and jumps in our face. He is a mini Aussie, so he can jump high. I have researched ways to help him not freak out so much when we leave. I read that giving him something like this with some yummy frozen in it like peanut butter, apple sauce, wet food, etc. so he relates us leaving to him getting a yummy treat. He still freaks out when we leave, but not as bad because he wants the kong but also wants to remind us he doesn’t approve of us leaving, lol. It’s Kong, so obviously very high quality. It’s pretty heavy. I wish there was an in between size, this is a little too big and the smaller size isn’t big enough. So his tongue can’t quite reach the end inside. He also plays with it when it’s not filled with treats. We have a few so one can be in the freezer while he has one. Thank goodness he is a dog that doesn’t destroy stuff when we are gone, just yells at us when we are leaving. After we are gone he just pouts. But this gives him something to do and keeps him busy. It takes him quite a while to finish what’s inside.
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Reviewed in the United States on March 24, 2026
★★★★★ 5
Tough
Size: X-Large (Pack of 1), Product Packaging: Standard Packaging
Nice and tough. Good, large size to put lots of treats and goodies to freeze for long interactive experience enjoyment.
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Reviewed in the United States on June 9, 2026
★★★★★ 4
Helps with separation anxiety, keeps dogs busy
Size: Medium (Pack of 1), Product Packaging: Standard Packaging
Have been using kongs for my labs for years. Brand new the kongs do have a strong rubber smell. Try putting the Kong in a pot with water over low fire to help reduce the smell. Stuff with favorite treats or fill with peanut butter and freeze. Will keep dogs busy and chewers with an indestructible toy
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Reviewed in the United States on March 17, 2026
★★★★★ 5
Very durable and my Dutchie loves it
Size: X-Large (Pack of 1), Product Packaging: Standard Packaging
This is one of many Kongs I have purchased through the years. This one was the extra large that was purchased for my Dutch Shepherd. Every night at bedtime, he gets his Kong stuffed with some dry food, treats, and a nubs bone to hold everything in place. He loves his Kong and runs for his crate at bedtime. Usually, he doesn’t eat the treats immediately. But sometime during the middle of the night, he will wake up and eat. Every Kong I have purchased through the years has been very durable. I highly recommend this product for all sizes of dogs.
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Reviewed in the United States on May 22, 2026
